Welcome to the MCCT!
Maastricht Consensus Conference on Thrombosis (MCCT) 2019
We welcome you to attend the third edition of the Maastricht Consensus Conference on Thrombosis in 2019!
Inspired by previous MCCT meetings, we propose “Thrombo-inflammation and cardiovascular disease”, as the overarching theme. The topic of Thrombo-inflammation is more than a hype. For example, two landmark studies published in 2017 provide evidence for the importance of thrombo-inflammation in atherothrombotic diseases (targeted inhibition of Il-1beta in the CANTOS study, combined antiplatelet and anticoagulant application in the COMPASS trial, both interventions reducing major cardiovascular outcomes in high risk patients with atherosclerosis).
Thrombo-inflammation recognizes the important interactions between inflammation and coagulation mechanisms, not only in host defense but also in a diversity of complex diseases. At the same time, it is also clear that we still lack knowledge on how this complex interplay works and how we can best interfere, in which patients and when?
Thrombo-inflammation has impact on organ reperfusion after ischemia as well as on microvascular integrity. All these aspects are pivotal in acute vascular pathologies like ischemic stroke, myocardial infarction and venous thromboembolism, but also in chronic conditions like atrial fibrillation, heart failure and post-thrombotic syndrome.
Complex disorders with high mortality and substantial longterm morbidity demand intensive clinical and translational research efforts to solve the many remaining questions.
We are delighted to, once again, introduce you to a panel of outstanding scientists, spanning the bench to bedside spectrum of research.
The MCCT formula will remain unchanged, based on close interactions among all participants, with the ultimate goal of drafting a consensus document to indicate the state-of-the-art, but more importantly, the avenues for research in the years ahead.
We are proud that the past consensus document (MCCT 2017) is now published in the February issue of Thrombosis and Haemostasis, which gives credit to the high impact that this meeting has achieved.
We look forward to another exciting meeting and hope to welcome you in Maastricht, February 13th, 2019!
On behalf of the LOC, Hugo ten Cate